Theoretically its possible to measure the size of each of the body fluid compartments by injecting substances that will stay in one compartment only the substance that attach to object. To measure total body water heavy water deuterium oxide tritiated water hto or antipyrene a drug that distributes throughout all of the body water is used as an indicator.
Fundamentals Study Guide 2 Fluid And Electrolytes Nsu
Measurement of body fluid compartments. Body fluids can be discussed in terms of their specific fluid compartment a location that is largely separate from another compartment by some form of a physical barrier. Compartment volumes are measured by determining the volume of distribution of a tracer substance. Measurement of body fluid compartments body fluid compartments can be measured by dilution of a compound that distributes only in the space of interest. The average volume of plasma in the average 70 kg male is approximately 35 liters. Intracellular fluid compartment 28 liters inside 75 trillion cells of body constitutes 40 of body weight composition of cell fluids remarkably similar even in different animals ranging from most primitive micro organisms to humans. Extracellular fluid ecf surrounds all cells in the body.
If the amount of the substance is known and the resulting concentration is measured the volume can be calculated. The intracellular fluid icf compartment is the system that includes all fluid enclosed in cells by their plasma membranes. Body fluids can be discussed in terms of their specific fluid compartment a location that is largely separate from another compartment by some form of a physical barrierthe intracellular fluid icf compartment is the system that includes all fluid enclosed in cells by their plasma membranesextracellular fluid ecf surrounds all cells in the body. After a 2 hr equilibration period a blood sample is withdrawn and the plasma is separated and analyzed for d2o. Body fluids can be discussed in terms of their specific fluid compartment a location that is largely separate from another compartment by some form of a physical barrierthe intracellular fluid icf compartment is the system that includes all fluid enclosed in cells by their plasma membranes. The blood represents both the intracellular compartment the fluid inside the blood cells and the extracellular compartment the blood plasma.
Body fluids can be discussed in terms of their specific fluid compartment a location that is largely separate from another compartment by some form of a physical barrierthe intracellular fluid icf compartment is the system that includes all fluid enclosed in cells by their plasma membranesextracellular fluid ecf surrounds all cells in the body. The indicator dilution principle is based on the definition of a concentration. The compartment volume is calculated as. A known amount of a tracer is added to a compartment. The tracer concentration in that compartment is measured after allowing sufficient time for uniform distribution throughout the compartment. We inject 30 ml of deuterium oxide d2o as an isotonic saline solution into an arm vein.
For example suppose we want to measure total body water in a 60 kg woman.
Gallery of Measurement Of Body Fluid Compartments
