According to the avma guidelines which statement is true for the use of co2 as a euthanasia agent of mice. Which statement is true about a records management system for clinical assessments of rodents.
Touch Free Measurement Of Body Temperature Using Close Up
Which statement is true about body temperature measurement in rodents. Heat sources should be modulated to a safe temperature. Which statement is true regarding care procedures for mice undergoing surgery. Start studying exercise 4. Lung function measurement techniques for rodents an overview. Learn vocabulary terms and more with flashcards games and other study tools. During the procedure mice should be monitored mainly for anesthesia body temperature and cardiovascular and respiratory function.
Many rodent studies have demonstrated different experimental outcomes due to differences in body temperature under anesthesia including studies of the heart brain liver and urogenital system. Although previous studies suggest that rectal measurement is stressful and results in long lasting elevations in body temperatures we evaluated how this procedure affects brain muscle skin and core temperatures measured with chronically implanted thermocouple electrodes in rats. On the other hand taking rectal temperature every hour suppressed the circadian rhythm of intraperitoneal temperature. Outbred stock tend to be more healthy and produce more young also called outbred vigor. Using these rats is sometimes desirable in scientific studies when genetic heterogeneity differences is not a concern. Which statement is true regarding care procedures for mice undergoing surgery.
Genetically dissimilar animals males and females that are not related are mated. In unhandled rats day temperature was about 357c and nocturnal temperature about 2c higher fig. In 1962 miles recorded temperature in rats by radio transmitters. During the procedure mice should be monitored mainly for depth of anesthesia cardiovascular and respiratory function. Which statement is true about supporting body temperature in anesthetized rodents. Among studies involving core and surface temperature measurements in mice the surface temperature is on average 257 c 34 c or 23 c lower than core temperature depending on the site.
16778595111119137 the technique used to measure body temperature is critical to the interpretation of an experiment due to the heterogeneity of temperature in different locations of the animals body ranging from the temperature of the tail to the animals true core temperature. Lung function is a relevant endpoint in pharmacological studies eg in models for asthma copd or infection in safety pharmacological studies performed according to the ich guideline s7a core battery part lung and follow up and finally in toxicological studies particularly if the airways are in the focus of interest. Rectal probe thermometry is commonly used to measure body core temperature in rodents because of its ease of use.